The mass cytometry (CyTOF) technology is a new technique that can bring new insights into complicated biological processes. It can generate a high-resolution map of the tumor microenvironment (TME) in various type of patient samples. In the case of multiple myeloma, the immunologic abnormality within the blood and bone marrow microenvironment is an important for understanding TME and developing more advanced treatment strategies.

· Deep profiling of the immune system of multiple myeloma

· Identification of immune microenvironment of multiple myeloma

· Biomarker discovery

· Understanding disease progression and response to specific therapy in serial patient samples